Lascufloxacin 75 mg, 50 tablets: profile, composition and research
Reference page for Lascufloxacin 75 mg, 50 tablets. Active substance: Ласкуфлоксацин / Lascufloxacin.
- What it is: lascufloxacin, an antibacterial from the later fluoroquinolone generation.
- Presentation: 75 mg tablets, 50 tablets per pack.
- Status: prescription-only medicine.
- Research: clinical work in community-acquired pneumonia, links below.
- Where to buy: APV Pharmacy (price and availability there).
Key facts
| Active substance | Lascufloxacin |
|---|---|
| Form | Tablets |
| Strength | 75 mg per tablet |
| Pack size | 50 tablets |
| Category | Prescription medicine |
| Article (SKU) |
What lascufloxacin is
Lascufloxacin is a synthetic antibacterial from the fluoroquinolone class. It was developed in Japan, where it is registered for bacterial infections of the respiratory tract. The substance belongs to the later fluoroquinolone generation: it was designed to keep its activity against strains that had already acquired resistance to earlier members of the class.
Fluoroquinolones have been used in medicine since the 1980s. Over that time bacteria developed defence mechanisms, so a new molecule inside the class matters: it gives a physician one more option when standard antibiotics no longer work.
The product is supplied as tablets. It is meant for systemic action: the substance is absorbed in the gut and distributed through the body, so it is used for infections rather than for the skin or mucosa alone.
How lascufloxacin works
The target
The drug acts on two enzymes of the bacterial cell: DNA gyrase and topoisomerase IV. Both keep the circular DNA molecule in the right shape while it is copied and the cell divides.
What happens to the bacterium
Once these enzymes are blocked, the bacterium can no longer copy its DNA and dies. The effect is called bactericidal: the drug does not merely stop growth, it breaks the cell.
Why it matters
Human DNA is built differently from bacterial DNA, so the action is selective. Even so, fluoroquinolones affect a number of processes in the body, which is why they are treated as medicines that need medical supervision.
Activity spectrum
Lascufloxacin acts on Gram-positive cocci, including pneumococcus and staphylococci, and on Gram-negative bacilli such as Escherichia coli and other enterobacteria.
That profile explains why the drug is considered mainly for respiratory infections: it covers the organisms most often involved in infections of the airways.
Approved uses
The manufacturer's prescribing information lists bacterial infections of the respiratory tract. The list of indications and the way the medicine is used are decided by a treating physician after examination, not by a reference page.
Giving an antibiotic without a confirmed bacterial infection makes no sense. Fluoroquinolones do not act on viruses, including those behind the common cold and influenza, so such treatment is useless in a viral infection.
Published research
Primary sources, verified against PubMed:
- Lascufloxacin switch therapy versus ampicillin/sulbactam for older patients with community-acquired pneumonia in Japan (STEP study): a study protocol, PubMed 42379706 (BMJ Open, 2026).
- Do current data justify the framing of respiratory fluoroquinolones and lascufloxacin in the 2024 JRS adult pneumonia guideline digest?, PubMed 42061138 (Respir Investig, 2026).
- Some Newer Antibiotics Active Against Helicobacter pylori and Anaerobic Bacteria and the Potential Benefits of Their Wider Availability, PubMed 42353704 (Antibiotics (Basel), 2026).
Listed for reference. Publication of a study is not a claim about this particular product.
Precautions
- This is a prescription medicine. Prescribing, dosing and monitoring belong to a physician.
- Fluoroquinolones may affect tendons, heart rhythm and the nervous system. Any unusual symptom during treatment should be reported to a doctor.
- In reduced kidney function the regimen is adjusted by a physician.
- Use during pregnancy or breastfeeding is discussed with a doctor individually.
- Tell your doctor about every other medicine you take: interactions are possible.
- An unfinished course of antibiotics helps resistant bacteria spread. The length of treatment is set by a physician.
Frequently asked
Is lascufloxacin a prescription medicine?
Yes. It is a prescription antibacterial and is not intended for self-medication.
Why does this page not give a dosing schedule?
The regimen depends on the type of infection, the patient's condition and kidney function. That is a physician's decision, not a reference page's.
Where does the order ship from?
Shipping and customs handling are described on the APV Pharmacy delivery page.