Mouse Nerve Growth Factor for Injection, 10 vials: profile, composition and research

Reference page for Mouse Nerve Growth Factor for Injection, 10 vials. Active substance: Фактор роста нервов (NGF) / Nerve growth factor (NGF).

Key facts

What this medicine is

Mouse Nerve Growth Factor for Injection is a biological medicine based on nerve growth factor (NGF), obtained from the tissue of mouse submandibular glands. It is not a synthetic molecule but a purified protein.

It is supplied as a lyophilised powder for solution for injection. Each vial holds 20 mcg (9000 U) of the active substance, and a pack contains 10 vials.

The medicine is made in China and used in neurology and rehabilitation medicine. It is a prescription product and is meant to be given by healthcare professionals.

How nerve growth factor acts

The target

NGF binds to TrkA receptors on the surface of neurons and sets off intracellular signalling pathways. These receptors are especially active in cells of the peripheral nervous system.

What happens in the cell

Activation of these pathways supports the survival of neurons, stimulates axon growth and helps maintain signal transmission along the nerve fibre.

Nerve repair

This creates the conditions for regeneration of damaged peripheral nerves. That mechanism is the basis of the medicine's use in neurology.

Approved uses

In the literature the product is mentioned in peripheral nerve injury, various types of neuropathy, recovery after spinal cord injury as part of combined therapy, after stroke, and in some neurological developmental disorders in children.

It is given intramuscularly, subcutaneously or near the lesion site according to a physician's protocol. Before injection the powder is dissolved in a sterile diluent.

Precautions

The medicine is contraindicated in hypersensitivity to NGF proteins and in a history of severe allergic reactions. In pregnancy and breastfeeding it is used only on a physician's instruction.

Local reactions at the injection site, allergic responses, a mild rise in temperature and occasional headache or fatigue are possible. Marked symptoms should be reported to a doctor.

It is kept in a refrigerator without freezing and dissolved only with a sterile diluent. Administration is carried out by a healthcare professional.

Published research

Primary sources, verified against PubMed:

• The Clinical Effect of a Combination of Mouse Nerve Growth Factor and Methylcobalamin to Treat Lumbar Disc Herniation with Foot Drop: A Retrospective Cohort Study., PubMed 34124841 (Orthop Surg, 2021).
• Mouse nerve growth factor promotes neurological recovery in patients with acute intracerebral hemorrhage: A proof-of-concept study., PubMed 32798840 (J Neurol Sci, 2020).
• Mouse Nerve Growth Factor Injection and Progression Rate in Patients With Amyotrophic Lateral Sclerosis: An Observational Study., PubMed 35250834 (Front Neurol, 2022).
• Acupuncture combined with mouse nerve growth factor in the treatment of peripheral facial palsies: systematic review and meta-analysis., PubMed 40951001 (Front Med (Lausanne), 2025).

Listed for reference. Publication of a study is not a claim about this particular product.

Precautions

• This is a prescription medicine and is given only by healthcare professionals.
• It is contraindicated in allergy to NGF proteins and in a history of severe allergic reactions.
• Use during pregnancy or breastfeeding is discussed with a doctor individually.
• Injection-site reactions, allergic responses, fever, headache and fatigue are possible.
• The powder must be dissolved only with a sterile diluent, and the product must be kept in a refrigerator without freezing.
• Tell your doctor about every other medicine you take: interactions are possible.

Frequently asked